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Ritonavir or lopinavir/ritonavir significantly increase plasma concentrations of oxycodone in healthier human volunteers on account of inhibition of CYP3A4 and CYP2D6.[58] Rifampicin considerably cuts down plasma concentrations of oxycodone on account of strong induction of CYP3A4.For those who have a feeding tube, the prolonged-release capsule con

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